Genetic diagnostics is the most efficient way to subtype metabolic disorders, providing the necessary information to make confident individualized treatment and management decisions. For example, in coenzyme Q10 deficiency, a correct diagnosis is important because some patients may show a favorable response to CoQ10 treatment.
22 diagnostic tests, covering 354 genes
associated with metabolic disorder
Comprehensive Metabolism Panel
The Blueprint Genetics Comprehensive Metabolism Panel
is a 355 gene diagnostic tool developed for patients
with clinical suspicion of inborn error of metabolism.
Our diagnostic process
From sample to clinical interpretation
Ordering and sample preparation
After receiving a patient’s medical history and sample we start the sample preparations in our CLIA certified laboratory.
We sequence the DNA in our lab with our proprietary targeted sequencing method OS-Seq™, developed at Stanford.
Data analysis and interpretation
We use our own proprietary automated bioinformatics pipeline to produce clinically relevant information - fast and reliably.
Our team of geneticists and clinicians produce a comprehensive clinical statement to support the diagnosis of your patient.
What genetic diagnostics can offer patients with metabolic disorders
Hundreds of inherited metabolic disorders have been identified, including disorders of lysosomal storage, fatty acid oxidation, creatine metabolism, glycosylation, glycogen storage and urea cycle, peroxisomal disorders, organic acidemias, hypoglycemia, hyperinsulinism and ketone metabolism deficiency, lipodystrophy, hyperphenylalaninemia, and mitochondrial DNA depletion. These medical conditions vary in severity and age of onset, but they can cause lifelong health problems or death. Early detection of congenital metabolic disorders is important to prevent the morbidity, mortality, and disabilities associated with the inherited disorder.
We offer comprehensive genetic diagnostics for hereditary metabolic disorders, also known as “inborn errors of metabolism.”